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An Overview of Statistical Issues and Methods of Meta-Analysis

 


JE Schmid, GG Koch, and LM LaVange
1991, Journal of Biopharmaceutical Statistics, 1,(1), 103-120

Keywords: Meta-analysis; random effects model; survey data regression; combination of studies

Abstract A meta-analysis is a statistical analysis of the data from some collection of studies in order to synthesize the results. In this paper we discuss issues that frequently arise in meta-analysis and give an overview of the methods used, with particular attention to the use of fixed- and random-effects approaches. The methods are then applied to two sample datasets.